Dabrafenib major avoid the concomitant use of dabrafenib, a cyp3a4 substrate, and isoniazid, inh a strong cyp3a4 inhibitor, as dabrafenib levels may increase.
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The katg 315thr mutation was observed in 74 of 131 isoniazid resistant isolates and more likely to be mdr-tb 48.
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Rhea isoniazid is an antibiotic that fights bacteria.
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