Ribeiro jm, lucas m, baptista a, victorino rmm fatal hepatitis associated with ranitidine.
Ranitidine was the result of a rational drug-design procedure and it became a refined theoretical account of quantitative structure-activity relationships qsar and histamine h2-receptor.
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The possibility of malignancy should be excluded before commencement of therapy in patients with gastric ulcer and if indications include dyspepsia; patients of middle age and over with new or recently changed dyspeptic symptoms must be included as treatment with ranitidine may mask symptoms of gastric carcinoma.
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The clinical significance of this triazolam and ranitidine pharmacokinetic interaction is unknown.
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76,156 in his study of the iv administration of these drugs 15 minutes before anesthetic induction, hong concluded that prophylactic ranitidine 50 mg iv and metoclopramide 10 mg iv may be an easy and useful method to decrease the volume while increasing the ph of gastric contents.
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ranitidine produced smaller, non-significant increases.