In flexible-dose studies, no new adverse events were observed in patients receiving 60 mg of paroxetine hydrochloride compared to any of the other treatment groups.
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a patient medication guide about antidepressant medicines, depression and other serious mental illness, and suicidal thoughts or actions is available for pexeva paroxetine mesylate .
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in a placebo-controlled study of elderly patients with major depressive disorder, 13 13 104 of patients treated with paroxetine hydrochloride controlled-release tablets discontinued due to an adverse event.
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paroxetine, a phenylpiperidine derivative, was originally developed in 1975 by jorgen buus-lassen and associates working in a small danish company ferrosan.
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due to the narrow therapeutic index of pimozide and its known ability to prolong the qt interval, concomitant use of pimozide and paroxetine hydrochloride is contraindicated see contraindications .
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The long-term efficacy of paroxetine in treating panic disorder has been demonstrated in a 24-week maintenance study with relapse prevention design 5 of patients receiving paroxetine 10-40mg daily relapsed, versus 30 of patients on placebo.
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