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signs of heart failure decompensation and congestion such as a persistent increase in resting respiratory rate or recurrence of cough may respond to an often temporary increase in furosemide dose.
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in one long-term study in patients with severe cardiac disease receiving 30-160 mg of furosemide daily, amiloride dosages of 20 mg daily usually maintained plasma potassium concentrations within the normal range; in 2 patients who developed hypokalemia at this dosage, 40 mg of amiloride daily was required.
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