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If bupropion is added to the treatment regimen of a patient already receiving a drug metabolized by cyp2d6, the need to decrease the dose of the original medication should be considered, particularly for those concomitant medications with a narrow therapeutic index.

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wellbutrin xl is contraindicated in patients with a current or prior diagnosis of bulimia or anorexia nervosa because of a higher incidence of seizures noted in patients treated for bulimia with the immediate-release formulation of bupropion.

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see the end of this medication guide for a complete list of ingredients in bupropion hydrochloride extended-release tablets xl .

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the seizure rate associated with doses of sustained release bupropion in depressed patients up to 300 mg per day is approximately 0.

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