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This is because methotrexate can cause birth defects or death to a fetus.

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ask your doctor about the safe use of alcoholic beverages while you are taking methotrexate.

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heparin, methotrexate, cyclosporine, warfarin, and phenytoin may all increase calcium losses, and 10 mg day of corticosteroids can cause osteopenia and hypercalciuria.

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ethinyl estradiol; levonorgestrel; folic acid; levomefolate moderate folic acid may compete with methotrexate for entry into cells.
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