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pharmacodynamic parameters were also measured and demonstrated that the change in inhibition of platelet aggregation was related to the change in the exposure to clopidogrel active metabolite.
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patients receiving lopid and complaining of muscle pain, tenderness, or weakness should have prompt medical evaluation for myositis, including serum creatine-kinase level determination.
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Aspirin followed by clopidogrel, compared with aspirin alone, was the optimal strategy for this population, with an icer of 1964 per qaly gained using the price of generic clopidogrel and a difference in costs of 185 and qalys of 0.
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